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Precious Metals

Ruthenium(II) complexes with 6-methyl-2-thiouracil selectively reduce cell proliferation, cause DNA double-strand break and trigger caspase-mediated apoptosis through JNK/p38 pathways in human acute promyelocytic leukemia cells

D.William
Synthesis of ruthenium(II) complexes with 6-methyl-2-thiouracil Ruthenium(II) complexes with 6-methyl-2-thiouracil ligand, cis-[Ru(6m2tu)2(PPh3)2] (1) and [Ru(6m2tu)2(dppb)] (2), were obtained as previously described by Correa20. Briefly, synthesis...